Reaction Details |
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Target | N-formyl peptide receptor 2 |
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Ligand | BDBM350511 |
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Substrate/Competitor | n/a |
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Meas. Tech. | FLIPR |
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EC50 | 14300±n/a nM |
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Citation | Beard, RL; Donello, JE; Viswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent US10208071 Publication Date 2/19/2019 |
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More Info.: | Get all data from this article, Assay Method |
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N-formyl peptide receptor 2 |
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Name: | N-formyl peptide receptor 2 |
Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 38968.35 |
Organism: | Homo sapiens (Human) |
Description: | P25090 |
Residue: | 351 |
Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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BDBM350511 |
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n/a |
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Name | BDBM350511 |
Synonyms: | US10208071, Compound 51 | US10208071, Table 1.8 | US10799518, Compound 51 | methyl 2-({[(4- iodophenyl)amino]carbonyl}amino)- 3-phenylpropanoate |
Type | Small organic molecule |
Emp. Form. | C16H15IN2O3 |
Mol. Mass. | 410.2064 |
SMILES | OC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(I)cc1 |r| |
Structure |
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