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TargetN-formyl peptide receptor 2
LigandBDBM350511
Substrate/Competitorn/a
Meas. Tech.FLIPR
EC50 14300±n/a nM
Citation Beard, RLDonello, JEViswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent US10208071 Publication Date 2/19/2019
More Info.:Get all data from this article,  Assay Method
 
N-formyl peptide receptor 2
Name:N-formyl peptide receptor 2
Synonyms:ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:38968.35
Organism:Homo sapiens (Human)
Description:P25090
Residue:351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM350511
n/a
NameBDBM350511
Synonyms:US10208071, Compound 51 | US10208071, Table 1.8 | US10799518, Compound 51 | methyl 2-({[(4- iodophenyl)amino]carbonyl}amino)- 3-phenylpropanoate
TypeSmall organic molecule
Emp. Form.C16H15IN2O3
Mol. Mass.410.2064
SMILESOC(=O)[C@H](Cc1ccccc1)NC(=O)Nc1ccc(I)cc1 |r|
Structure
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