| Reaction Details |
|---|
 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
|---|
| Ligand | BDBM350552 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | FLIPR |
|---|
| EC50 | 4000±n/a nM |
|---|
| Citation |  Beard, RL; Donello, JE; Viswanath, V Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases US Patent US10208071 Publication Date 2/19/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| N-formyl peptide receptor 2 |
|---|
| Name: | N-formyl peptide receptor 2 |
|---|
| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 38968.35 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P25090 |
|---|
| Residue: | 351 |
|---|
| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
|
|
|
|---|
| BDBM350552 |
|---|
| n/a |
|---|
| Name | BDBM350552 |
|---|
| Synonyms: | US10208071, Compound 14 | rel-(2R,3S)-3-[(4- bromophenyl)carbamoyl] spiro[bicyclo[2.2.1]heptane- 7,1'-cyclopropane]-2-carboxylic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H18BrNO3 |
|---|
| Mol. Mass. | 364.234 |
|---|
| SMILES | OC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1 |TLB:9:8:6.5:19,THB:1:3:6.5:19| |
|---|
| Structure | 
|
|---|
Search and Browse
