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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Indoleamine 2,3-dioxygenase 1 | ||
| Ligand | BDBM370516 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzymatic IDO Assay | ||
| IC50 | 550±n/a nM | ||
| Citation |  Mautino, M; Kumar, S; Waldo, J; Jaipuri, F; Kesharwani, T; Zhang, X IDO inhibitors US Patent US10233190 Publication Date 3/19/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Indoleamine 2,3-dioxygenase 1 | |||
| Name: | Indoleamine 2,3-dioxygenase 1 | ||
| Synonyms: | I23O1_HUMAN | IDO | IDO-1 | IDO1 | INDO | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine 2,3-dioxygenase | Indoleamine-pyrrole 2,3-dioxygenase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 45330.80 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P14902 | ||
| Residue: | 403 | ||
| Sequence: |
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| BDBM370516 | |||
| n/a | |||
| Name | BDBM370516 | ||
| Synonyms: | 4-(1-hydroxy-2-(5H-imidazo[5,1-a]isoindol-5- yl)ethyl)cyclohexanecarboxylic acid | US10233190, Example 1436 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H22N2O3 | ||
| Mol. Mass. | 326.3896 | ||
| SMILES | OC(CC1c2ccccc2-c2cncn12)C1CCC(CC1)C(O)=O |(-.46,-1.48,;-.06,.01,;-1.15,1.1,;-2.63,.7,;-4.01,1.4,;-4.4,2.89,;-5.89,3.28,;-6.98,2.19,;-6.58,.71,;-5.1,.31,;-4.4,-1.06,;-4.64,-2.58,;-3.26,-3.28,;-2.18,-2.19,;-2.88,-.82,;1.43,.41,;2.52,-.68,;4.01,-.28,;4.4,1.2,;3.32,2.29,;1.83,1.89,;5.89,1.6,;6.98,.51,;6.29,3.09,)| | ||
| Structure | 
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