| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM261752 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Test for Antagonism |
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| Temperature | 298.15±n/a K |
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| IC50 | 5.59±n/a nM |
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| Comments | extracted |
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| Citation |  Peters, O; Bräuer, N; Blume, T; Ter Laak, A; Zorn, L; Nagel, J; Kaulfuss, S; Langer, G; Kuhnke, J Benzimidazole derivatives as EP4 antagonists US Patent US9708311 Publication Date 7/18/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 53134.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35408 |
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| Residue: | 488 |
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| Sequence: | MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
LNLSEKCI
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| BDBM261752 |
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| n/a |
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| Name | BDBM261752 |
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| Synonyms: | 3-Amino-4-[(2-methoxyethyl)amino]benzoic acid | US9708311, 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H14N2O3 |
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| Mol. Mass. | 210.2298 |
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| SMILES | COCCNc1ccc(cc1N)C(O)=O |
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| Structure | 
|
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