Reaction Details |
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Target | Free fatty acid receptor 4 |
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Ligand | BDBM382130 |
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Substrate/Competitor | n/a |
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Meas. Tech. | BRET assay |
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EC50 | 2750±n/a nM |
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Citation | Kumar, S; Sharma, R; Deore, VB; Yewalkar, NN Substituted phenyl alkanoic acid compounds as GPR120 agonists and uses thereof US Patent US10273230 Publication Date 4/30/2019 |
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More Info.: | Get all data from this article, Assay Method |
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Free fatty acid receptor 4 |
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Name: | Free fatty acid receptor 4 |
Synonyms: | FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4 |
Type: | PROTEIN |
Mol. Mass.: | 42256.91 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1508994 |
Residue: | 377 |
Sequence: | MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVC
ALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTL
SGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVV
PQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDA
RAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITI
LLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGA
ILTDTSVKRNDLSIISG
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BDBM382130 |
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n/a |
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Name | BDBM382130 |
Synonyms: | 4-(4-((2-(6-amino-5-(trifluoromethyl)pyridin-3-yl)cyclohex-1-en-1-yl)methoxy)phenyl)butanoic Acid | US10273230, Compound of Example 8 |
Type | Small organic molecule |
Emp. Form. | C23H25F3N2O3 |
Mol. Mass. | 434.4514 |
SMILES | Nc1ncc(cc1C(F)(F)F)C1=C(COc2ccc(CCCC(O)=O)cc2)CCCC1 |c:12| |
Structure |
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