| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM382178 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 0.646±n/a nM |
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| Citation |  Micheli, F; Cremonesi, S; Semeraro, T; Tarsi, L Substituted hexahydropyrrolo[3,4-b]pyrroles and hexahydrocyclopenta[c]pyrroles as dopamine receptor modulators US Patent US10273244 Publication Date 4/30/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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|
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| BDBM382178 |
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| n/a |
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| Name | BDBM382178 |
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| Synonyms: | US10273244, Example 10 | US10584135, Example 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27N7OS |
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| Mol. Mass. | 449.572 |
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| SMILES | Cc1ncoc1-c1nnc(SCCCN2C[C@@H]3CCN([C@@H]3C2)c2cccc(c2)C#N)n1C |r| |
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| Structure | 
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