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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Ghrelin O-acyltransferase | ||
| Ligand | BDBM396165 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | hGOAT Activity in HEK293 Cells after Incubation | ||
| IC50 | 0.110±n/a nM | ||
| Citation |  Godbout, C; Trieselmann, T; Vintonyak, V Oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors US Patent US10308667 Publication Date 6/4/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Ghrelin O-acyltransferase | |||
| Name: | Ghrelin O-acyltransferase | ||
| Synonyms: | GOAT | Ghrelin O-acyltransferase (GOAT) | MBOA4_HUMAN | MBOAT4 | Membrane-bound O-acyltransferase domain-containing protein 4 | O-acyltransferase domain-containing protein 4 | OACT4 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 49733.10 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q96T53 | ||
| Residue: | 435 | ||
| Sequence: |
| ||
| BDBM396165 | |||
| n/a | |||
| Name | BDBM396165 | ||
| Synonyms: | 6-[6-Amino-5-(2,4-dimethyl-2H-pyrazol-3-yl)-pyridin-2-ylmethyl]-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-ylamine | US10308667, Example 68 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H18N8O | ||
| Mol. Mass. | 350.3778 | ||
| SMILES | Cc1cnn(C)c1-c1ccc(Cc2c(C)nc3nonc3c2N)nc1N |(6.53,.81,;6.13,-.68,;7.04,-1.93,;6.13,-3.17,;4.67,-2.69,;3.33,-3.47,;4.67,-1.15,;3.33,-.38,;2,-1.15,;.67,-.38,;.67,1.15,;-.67,1.93,;-2,1.15,;-2,-.38,;-.67,-1.15,;-3.33,-1.15,;-4.67,-.38,;-6.13,-.86,;-7.04,.38,;-6.13,1.63,;-4.67,1.15,;-3.33,1.93,;-3.33,3.47,;2,1.93,;3.33,1.15,;4.67,1.93,)| | ||
| Structure | 
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