| Reaction Details |
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 | Report a problem with these data |
| Target | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial |
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| Ligand | BDBM263614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Submitochondrial Particle Assay |
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| pH | 7.4±n/a |
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| IC50 | <100.0±n/a nM |
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| Comments | extracted |
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| Citation |  Cesati, RR; Radeke, HS; Pandey, SK; Purohit, A; Robinson, SP Compositions, methods, and systems for the synthesis and use of imaging agents US Patent US9713651 Publication Date 7/25/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial |
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| Name: | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial |
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| Synonyms: | CI-51kD | Complex I-51kD | NADH dehydrogenase flavoprotein 1 | NADH-ubiquinone oxidoreductase 51 kDa subunit | NDUFV1 | NDUV1_BOVIN | UQOR1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50659.85 |
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| Organism: | Bos taurus |
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| Description: | EBI_100771 |
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| Residue: | 464 |
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| Sequence: | MLAARRLLGGSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGAQSRG
DWYKTKEILLKGPDWILGEVKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEG
EPGTCKDREIIRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAG
LIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPT
TVANVETVAVSPTICRRGGAWFASFGRERNSGTKLFNISGHVNNPCTVEEEMSVPLKELI
EKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALIQAQTGLGTAAVIVMDRS
TDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIE
GHTICALGDGAAWPVQGLIRHFRPELEERMQQFAQQHQARQAAF
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| BDBM263614 |
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| n/a |
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| Name | BDBM263614 |
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| Synonyms: | 2-fluoroethyl 4-(((1-(tert-butyl)-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)oxy)methyl)benzoate | US9713651, 45 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20ClFN2O4 |
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| Mol. Mass. | 382.814 |
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| SMILES | CC(C)(C)n1ncc(OCc2ccc(cc2)C(=O)OCCF)c(Cl)c1=O |
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| Structure | 
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