| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM397466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Receptor Binding Assay |
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| EC50 | 0.037±0.00 nM |
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| Citation |  Tafesse, L 7-beta-alkyl analogs of orvinols US Patent US9988392 Publication Date 6/5/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
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|
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| BDBM397466 |
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| n/a |
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| Name | BDBM397466 |
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| Synonyms: | US9988392, Compound 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H37NO5 |
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| Mol. Mass. | 491.6185 |
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| SMILES | COC12CC[C@@]3(C[C@]1(C)COCc1ccoc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,TLB:9:7:27.26:4.3,8:7:27.26:4.3| |
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| Structure | 
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