| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H3 receptor |
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| Ligand | BDBM397494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Binding Assay |
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| Ki | 30±n/a nM |
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| Citation |  Bartáné Szalai, G; Wágner, GA; Kiss, B; Schmidt, null; Balázs, O; Nagy, N H3 antagonists containing phenoxypiperidine core structure US Patent US9994525 Publication Date 6/12/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histamine H3 receptor |
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| Name: | Histamine H3 receptor |
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| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 48607.98 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 445 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
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| BDBM397494 |
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| n/a |
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| Name | BDBM397494 |
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| Synonyms: | US9994525, Example 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H38N2O4 |
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| Mol. Mass. | 418.5695 |
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| SMILES | C[C@@H]1CCCN1CCCOc1ccc(OC2CCN(CC2)C(=O)OC(C)(C)C)cc1 |r| |
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| Structure | 
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