| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM35489 |
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| Substrate/Competitor | Z-Arg-Arg-AMC |
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| Meas. Tech. | Cathepsin B mixture HTS dose-response confirmation |
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| pH | 6.8±n/a |
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| Temperature | 296.15±n/a K |
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| IC50 | 2120.02±n/a nM |
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| Citation |  PubChem, PC Cathepsin B mixture HTS dose-response confirmation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Cathepsin B |
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| Name: | Cathepsin B |
|---|
| Synonyms: | APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 37819.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_63102437 |
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| Residue: | 339 |
|---|
| Sequence: | MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW
NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
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|
|
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| BDBM35489 |
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| Z-Arg-Arg-AMC |
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| Name: | Z-Arg-Arg-AMC |
|---|
| Synonyms: | Benzyloxycarbonyl- L-arginyl- L-arginine- 4-methylcoumaryl-7-amide |
|---|
| Type: | fluorogenic substrate |
|---|
| Mol. Mass.: | 358.43 |
|---|
| Organism: | n/a |
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| Description: | n/a |
|---|
| Residue: | 3 |
|---|
| Sequence: | |
|---|
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