| Reaction Details |
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 | Report a problem with these data |
| Target | Malignant T-cell-amplified sequence 1 |
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| Ligand | BDBM403142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MTT assay |
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| EC50 | <20.0±n/a nM |
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| Citation |  Bannister, TD; Roush, WR; Choi, JY; Nair, R; Tsai, AS; Mishra, JK; Cleveland, JL Heterocyclic inhibitors of monocarboxylate transporter US Patent US10329303 Publication Date 6/25/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Malignant T-cell-amplified sequence 1 |
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| Name: | Malignant T-cell-amplified sequence 1 |
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| Synonyms: | MCT-1 | MCT1 | MCTS1 | MCTS1_HUMAN | Multiple copies T-cell malignancies |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 20563.62 |
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| Organism: | Homo sapiens (human) |
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| Description: | n/a |
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| Residue: | 181 |
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| Sequence: | MFKKFDEKENVSNCIQLKTSVIKGIKNQLIEQFPGIEPWLNQIMPKKDPVKIVRCHEHIE
ILTVNGELLFFRQREGPFYPTLRLLHKYPFILPHQQVDKGAIKFVLSGANIMCPGLTSPG
AKLYPAAVDTIVAIMAEGKQHALCVGVMKMSAEDIEKVNKGIGIENIHYLNDGLWHMKTY
K
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| BDBM403142 |
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| n/a |
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| Name | BDBM403142 |
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| Synonyms: | US10329303, Example 15 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H28N4O3S |
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| Mol. Mass. | 452.569 |
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| SMILES | CC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(-c3cccc(CO)c3)c2c(=O)n(C)c1=O |
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| Structure | 
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