| Reaction Details |
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 | Report a problem with these data |
| Target | fMet-Leu-Phe receptor |
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| Ligand | BDBM37649 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands |
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| IC50 | 14700±n/a nM |
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| Citation |  PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| fMet-Leu-Phe receptor |
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| Name: | fMet-Leu-Phe receptor |
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| Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38456.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4503779 |
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| Residue: | 350 |
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| Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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| BDBM37649 |
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| n/a |
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| Name | BDBM37649 |
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| Synonyms: | 2-(4-bromophenyl)-3-(furan-2-carbonyl)-4-hydroxy-1-(3-methoxypropyl)-2H-pyrrol-5-one | 2-(4-bromophenyl)-3-(furan-2-ylcarbonyl)-1-(3-methoxypropyl)-4-oxidanyl-2H-pyrrol-5-one | 2-(4-bromophenyl)-3-[2-furanyl(oxo)methyl]-4-hydroxy-1-(3-methoxypropyl)-2H-pyrrol-5-one | 5-(4-bromophenyl)-4-(2-furoyl)-3-hydroxy-1-(3-methoxypropyl)-3-pyrrolin-2-one | MLS000036754 | SMR000058000 | cid_661728 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18BrNO5 |
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| Mol. Mass. | 420.254 |
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| SMILES | COCCCN1C(C(C(=O)c2ccco2)C(=O)C1=O)c1ccc(Br)cc1 |
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| Structure | 
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