Reaction Details |
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Target | fMet-Leu-Phe receptor |
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Ligand | BDBM37663 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands |
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IC50 | 20800±n/a nM |
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Citation | PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay(2007)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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fMet-Leu-Phe receptor |
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Name: | fMet-Leu-Phe receptor |
Synonyms: | FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 38456.14 |
Organism: | Homo sapiens (Human) |
Description: | gi_4503779 |
Residue: | 350 |
Sequence: | METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVT
TISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNF
SPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPL
RVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPML
YVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
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BDBM37663 |
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n/a |
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Name | BDBM37663 |
Synonyms: | 4-[(E)-[4,5-diketo-1-(2-morpholinoethyl)-2-(3-pyridyl)pyrrolidin-3-ylidene]-hydroxy-methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid methyl ester | 4-[(E)-hydroxy-[1-[2-(4-morpholinyl)ethyl]-4,5-dioxo-2-(3-pyridinyl)-3-pyrrolidinylidene]methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylic acid methyl ester | MLS000081511 | SMR000044022 | cid_5389675 | methyl 3,5-dimethyl-4-[(E)-[1-(2-morpholin-4-ylethyl)-4,5-bis(oxidanylidene)-2-pyridin-3-yl-pyrrolidin-3-ylidene]-oxidanyl-methyl]-1H-pyrrole-2-carboxylate | methyl 4-[(E)-hydroxy-[1-(2-morpholin-4-ylethyl)-4,5-dioxo-2-pyridin-3-ylpyrrolidin-3-ylidene]methyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate |
Type | Small organic molecule |
Emp. Form. | C24H28N4O6 |
Mol. Mass. | 468.5023 |
SMILES | COC(=O)c1[nH]c(C)c(C(=O)C2C(N(CCN3CCOCC3)C(=O)C2=O)c2cccnc2)c1C |
Structure |
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