| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 1 |
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| Ligand | BDBM35373 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing |
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| IC50 | 45582±n/a nM |
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| Citation |  PubChem, PC In vitro MKP-1 Phosphatase Dose Response Active/Probe Assessment Assay - Reproducibility testing PubChem Bioassay(2006)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 1 |
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| Name: | Dual specificity protein phosphatase 1 |
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| Synonyms: | CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1 |
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| Type: | Protein phosphatase |
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| Mol. Mass.: | 39301.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_4758204 |
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| Residue: | 367 |
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| Sequence: | MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF
LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF
LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA
IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS
FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP
ITTSPSC
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| BDBM35373 |
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| n/a |
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| Name | BDBM35373 |
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| Synonyms: | 1-butyl-2-[2-(2,4-dimethoxyphenyl)-2-oxidanylidene-ethyl]sulfanyl-benzimidazole-5-sulfonamide | 1-butyl-2-[2-(2,4-dimethoxyphenyl)-2-oxoethyl]sulfanylbenzimidazole-5-sulfonamide | 1-butyl-2-[[2-(2,4-dimethoxyphenyl)-2-keto-ethyl]thio]benzimidazole-5-sulfonamide | 1-butyl-2-[[2-(2,4-dimethoxyphenyl)-2-oxoethyl]thio]-5-benzimidazolesulfonamide | MLS000055142 | SMR000066776 | cid_2997788 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N3O5S2 |
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| Mol. Mass. | 463.57 |
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| SMILES | CCCCn1c(SCC(=O)c2ccc(OC)cc2OC)nc2cc(ccc12)S(N)(=O)=O |
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| Structure | 
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