| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Ligand | BDBM36913 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) |
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| IC50 | >15.09±n/a nM |
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| Citation |  PubChem, PC Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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| Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63033.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101591 |
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| Residue: | 556 |
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| Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
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| BDBM36913 |
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| n/a |
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| Name | BDBM36913 |
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| Synonyms: | 2-[(2,5-dimethyl-1-pyridin-2-yl-pyrrol-3-yl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one | 2-[(2,5-dimethyl-1-pyridin-2-ylpyrrol-3-yl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one | 2-[[2,5-dimethyl-1-(2-pyridinyl)-3-pyrrolyl]methylidene]-1-thiazolo[3,2-a]benzimidazolone | 2-[[2,5-dimethyl-1-(2-pyridyl)pyrrol-3-yl]methylene]thiazolo[3,2-a]benzimidazol-1-one | MLS000036977 | SMR000036002 | cid_661826 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N4OS |
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| Mol. Mass. | 372.443 |
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| SMILES | Cc1cc(C=c2sc3nc4ccccc4n3c2=O)c(C)n1-c1ccccn1 |
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| Structure | 
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