Reaction Details | |||
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Target | Steroidogenic factor 1 | ||
Ligand | BDBM50090910 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Counterscreen for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) | ||
IC50 | 519±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Steroidogenic factor 1 | |||
Name: | Steroidogenic factor 1 | ||
Synonyms: | AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP | ||
Type: | Nuclear Hormone Receptor | ||
Mol. Mass.: | 51643.43 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 461 | ||
Sequence: |
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BDBM50090910 | |||
n/a | |||
Name | BDBM50090910 | ||
Synonyms: | 3alpha,16,17,18-tetrahydroxyaphidicolone | 6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7R)-tetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol | 6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7R,10S,12R,13R)-tetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol (Aphidicolin) | 6,13-di(hydroxymethyl)-2,6-dimethyl-(1S,2S,5R,6R,7R,10S,12R,13R)-tetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol(Aphidicolin) | CHEMBL29711 | aphidicholin | aphidicolin | cid_457964 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H34O4 | ||
Mol. Mass. | 338.4816 | ||
SMILES | C[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H]1CC[C@H]1C[C@@H]3C[C@]21CC[C@]3(O)CO |r| | ||
Structure | ![]() |