| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
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| Ligand | BDBM34164 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 |
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| IC50 | 4450±600 nM |
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| Citation |  PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-related protein A1 |
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| Name: | Bcl-2-related protein A1 |
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| Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
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| Type: | Apoptosis regulator protein |
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| Mol. Mass.: | 19909.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | gi_11024684 |
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| Residue: | 172 |
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| Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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| BDBM34164 |
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| n/a |
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| Name | BDBM34164 |
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| Synonyms: | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-2-quinolinone | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-carbostyril | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxy-quinolin-2-one | (3E)-3-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-ylidene]-6-methoxyquinolin-2-one | 3-[5-(4-Fluoro-phenyl)-[1,2,4]oxadiazol-3-yl]-6-methoxy-quinolin-2-ol | MLS000071054 | SMR000015028 | cid_5423532 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H12FN3O3 |
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| Mol. Mass. | 337.3046 |
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| SMILES | COc1ccc2[nH]c(=O)c(cc2c1)-c1noc(n1)-c1ccc(F)cc1 |
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| Structure | 
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