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TargetBcl-2-related protein A1
LigandBDBM34191
Substrate/Competitorn/a
Meas. Tech.TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1
IC50 4600±820 nM
Citation PubChem, PC TR-FRET secondary assay for HTS discovery of chemical inhibitors of anti-apoptotic protein Bfl-1 PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:Apoptosis regulator protein
Mol. Mass.:19909.74
Organism:Mus musculus (Mouse)
Description:gi_11024684
Residue:172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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BDBM34191
n/a
NameBDBM34191
Synonyms:(2-methoxyphenyl)-(3-methylsulfanyl-6,7-dihydro-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-6-yl)methanone | (2-methoxyphenyl)-[3-(methylthio)-6,7-dihydro-[1,2,4]triazino[5,6-d][3,1]benzoxazepin-6-yl]methanone | MLS000111412 | SMR000107336 | cid_2906776
TypeSmall organic molecule
Emp. Form.C19H16N4O3S
Mol. Mass.380.42
SMILESCOc1ccccc1C(=O)C1Nc2ccccc2-c2nnc(SC)nc2O1
Structure
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