BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSteroidogenic factor 1
LigandBDBM39521
Substrate/Competitorn/a
Meas. Tech.Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50 3284±n/a nM
Citation PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Steroidogenic factor 1
Name:Steroidogenic factor 1
Synonyms:AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:Nuclear Hormone Receptor
Mol. Mass.:51643.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39521
n/a
NameBDBM39521
Synonyms:(3-Cyano-7-ethoxy-quinolin-2-ylsulfanyl)-acetic acid ethyl ester | 2-[(3-cyano-7-ethoxy-2-quinolinyl)thio]acetic acid ethyl ester | 2-[(3-cyano-7-ethoxy-2-quinolyl)thio]acetic acid ethyl ester | MLS000032271 | SMR000002489 | cid_650479 | ethyl 2-(3-cyano-7-ethoxy-quinolin-2-yl)sulfanylethanoate | ethyl 2-(3-cyano-7-ethoxyquinolin-2-yl)sulfanylacetate
TypeSmall organic molecule
Emp. Form.C16H16N2O3S
Mol. Mass.316.375
SMILESCCOC(=O)CSc1nc2cc(OCC)ccc2cc1C#N
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: