BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSteroidogenic factor 1
LigandBDBM39554
Substrate/Competitorn/a
Meas. Tech.Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1)
EC50 27310±n/a nM
Citation PubChem, PC Counterscreen for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA): A cell-based dose-response assay for inhibition of the Steroidogenic Factor 1 (SF-1) PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Steroidogenic factor 1
Name:Steroidogenic factor 1
Synonyms:AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:Nuclear Hormone Receptor
Mol. Mass.:51643.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
QRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39554
n/a
NameBDBM39554
Synonyms:2-(2-furanylmethylamino)-10-pyridazino[6,1-b]quinazolinone | 2-(2-furfurylamino)pyridazino[6,1-b]quinazolin-10-one | 2-(furan-2-ylmethylamino)pyridazino[6,1-b]quinazolin-10-one | 2-[(2-furylmethyl)amino]-10H-pyridazino[6,1-b]quinazolin-10-one | MLS000094230 | SMR000029820 | cid_3243853
TypeSmall organic molecule
Emp. Form.C16H12N4O2
Mol. Mass.292.2921
SMILESO=c1c2ccccc2nc2ccc(NCc3ccco3)nn12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: