| Reaction Details |
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 | Report a problem with these data |
| Target | Focal adhesion kinase 1 |
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| Ligand | BDBM41021 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response biochemical assay for inhibitors of Focal Adhesion Kinase (FAK) |
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| IC50 | 3018±n/a nM |
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| Citation |  PubChem, PC Dose-response biochemical assay for inhibitors of Focal Adhesion Kinase (FAK) PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Focal adhesion kinase 1 |
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| Name: | Focal adhesion kinase 1 |
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| Synonyms: | FADK 1 | FAK | FAK1 | FAK1_HUMAN | FLT4 | FRNK | Focal adhesion kinase (FAK) | Focal adhesion kinase (PTK2) | Focal adhesion kinase 1 (FAK) | Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 | Focal adhesion kinase-related nonkinase | PPP1R71 | PTK2 | Protein phosphatase 1 regulatory subunit 71 | Protein-tyrosine kinase 2 | VHL/Focal adhesion kinase 1 | p125FAK | pp125FAK |
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| Type: | Tyrosine-protein kinase |
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| Mol. Mass.: | 119233.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q05397 |
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| Residue: | 1052 |
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| Sequence: | MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGD
ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQ
TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFII
RPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRE
RIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDH
PHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESK
RFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFT
SASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWA
YDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGY
PSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQE
IAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLS
RGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNE
GVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA
LRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM
LTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
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| BDBM41021 |
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| n/a |
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| Name | BDBM41021 |
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| Synonyms: | (3Z)-3-(p-anisidinomethylene)oxindole | (3Z)-3-[(4-methoxyanilino)methylidene]-1H-indol-2-one | (3Z)-3-[[(4-methoxyphenyl)amino]methylidene]-1H-indol-2-one | 3-{[(4-methoxyphenyl)amino]methylene}-1,3-dihydro-2H-indol-2-one | MLS000530407 | SMR000135384 | cid_5657027 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2O2 |
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| Mol. Mass. | 266.2946 |
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| SMILES | COc1ccc(cc1)N=CC1C(=O)Nc2ccccc12 |w:8.8| |
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| Structure | 
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