| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM35489 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cathepsin B dose-response confirmation |
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| IC50 | 2120±127.5 nM |
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| Citation |  PubChem, PC Cathepsin B dose-response confirmation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 37819.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_63102437 |
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| Residue: | 339 |
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| Sequence: | MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW
NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
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| BDBM35489 |
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| n/a |
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| Name | BDBM35489 |
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| Synonyms: | 1-Acetyl-3-(3,4-dichloro-5-oxo-2,5-dihydro-furan-2-yl)-urea | MLS000035450 | N-[(3,4-dichloro-5-keto-2H-furan-2-yl)carbamoyl]acetamide | N-[(3,4-dichloro-5-oxo-2H-furan-2-yl)carbamoyl]acetamide | N-[[(3,4-dichloro-5-oxo-2H-furan-2-yl)amino]-oxomethyl]acetamide | N-[[3,4-bis(chloranyl)-5-oxidanylidene-2H-furan-2-yl]carbamoyl]ethanamide | SMR000001295 | cid_654815 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H6Cl2N2O4 |
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| Mol. Mass. | 253.04 |
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| SMILES | CC(=O)NC(=O)NC1OC(=O)C(Cl)=C1Cl |c:12| |
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| Structure | 
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