| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ephrin type-B receptor 4 |
|---|
| Ligand | BDBM41455 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose-response biochemical assay for antagonists of the interaction between the Eph receptor B4 (EphB4) and its ligand ephrin-B2 via TNYL-RAW peptide |
|---|
| IC50 | >79400±n/a nM |
|---|
| Citation |  PubChem, PC Dose-response biochemical assay for antagonists of the interaction between the Eph receptor B4 (EphB4) and its ligand ephrin-B2 via TNYL-RAW peptide PubChem Bioassay(2007)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Ephrin type-B receptor 4 |
|---|
| Name: | Ephrin type-B receptor 4 |
|---|
| Synonyms: | EPHB4 | EPHB4_HUMAN | Ephrin receptor | Ephrin type-B receptor 4 precursor (Tyrosine-protein kinase receptor HTK). | HTK | Hepatoma transmembrane kinase | MYK1 | TYRO11 | Tyrosine-protein kinase TYRO11 | VHL/Ephrin type-B receptor 4 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 108273.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P54760 |
|---|
| Residue: | 987 |
|---|
| Sequence: | MELRVLLCWASLAAALEETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEV
CDVQRAPGQAHWLRTGWVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDA
DTATALTPAWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQD
QGACMALLSLHLFYKKCAQLTVNLTRFPETVPRELVVPVAGSCVVDAVPAPGPSPSLYCR
EDGQWAEQPVTGCSCAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSA
VCQCRVGYFRARTDPRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALR
CRECRPGGSCAPCGGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPV
PFEPVNVTTDREVPPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPS
SVRFLKTSENRAELRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLDESEGWREQLAL
IAGTAVVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPN
EAVREFAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRRE
FLSEASIMGQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGM
LRGIASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGG
KIPIRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLP
PPPDCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIVARENGGASHPLLD
QRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRIGVTLAGHQKK
ILASVQHMKSQAKPGTPGGTGGPAPQY
|
|
|
|---|
| BDBM41455 |
|---|
| n/a |
|---|
| Name | BDBM41455 |
|---|
| Synonyms: | 5-(2-azepan-1-yl-2-oxoethyl)-1-(4-methylphenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | 5-[2-(1-azepanyl)-2-oxoethyl]-1-(4-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinone | 5-[2-(azepan-1-yl)-2-keto-ethyl]-1-(p-tolyl)pyrazolo[3,4-d]pyrimidin-4-one | 5-[2-(azepan-1-yl)-2-oxidanylidene-ethyl]-1-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-one | 5-[2-(azepan-1-yl)-2-oxoethyl]-1-(4-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-one | MLS000093731 | SMR000029349 | cid_3239246 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23N5O2 |
|---|
| Mol. Mass. | 365.4289 |
|---|
| SMILES | Cc1ccc(cc1)-n1ncc2c1ncn(CC(=O)N1CCCCCC1)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
