Reaction Details |
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Target | Sphingosine 1-phosphate receptor 2 |
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Ligand | BDBM31041 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor |
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IC50 | 2530±n/a nM |
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Citation | PubChem, PC Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor PubChem Bioassay(2007)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Sphingosine 1-phosphate receptor 2 |
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Name: | Sphingosine 1-phosphate receptor 2 |
Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 38883.16 |
Organism: | Homo sapiens (Human) |
Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
Residue: | 353 |
Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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BDBM31041 |
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n/a |
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Name | BDBM31041 |
Synonyms: | 3-Bromo-4-chloro-7-diethylamino-chromen-2-one | 3-bromanyl-4-chloranyl-7-(diethylamino)chromen-2-one | 3-bromo-4-chloro-7-(diethylamino)-1-benzopyran-2-one | 3-bromo-4-chloro-7-(diethylamino)chromen-2-one | 3-bromo-4-chloro-7-(diethylamino)coumarin | MLS000029629 | SMR000001240 | cid_648878 |
Type | Small organic molecule |
Emp. Form. | C13H13BrClNO2 |
Mol. Mass. | 330.605 |
SMILES | CCN(CC)c1ccc2c(Cl)c(Br)c(=O)oc2c1 |
Structure |
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