| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 2 |
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| Ligand | BDBM36900 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor |
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| IC50 | 3905±n/a nM |
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| Citation |  PubChem, PC Dose Response Cell Based Assay for Antagonists of the S1P2 Receptor PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sphingosine 1-phosphate receptor 2 |
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| Name: | Sphingosine 1-phosphate receptor 2 |
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| Synonyms: | EDG5 | S1P2 | S1PR2 | S1PR2_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-5 | Sphingosine-1-phosphate receptor 2 | ndothelial differentiation G-protein coupled receptor 5 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38883.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Membranes isolated from S1P2-transfected CHO cells were used in ligand binding assay. |
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| Residue: | 353 |
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| Sequence: | MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVAR
NSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASV
FSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACS
TVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLG
VFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVL
RPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
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| BDBM36900 |
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| n/a |
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| Name | BDBM36900 |
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| Synonyms: | 4-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-8-fluoro-5H-pyrimido[5,4-b]indole | 4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-8-fluoranyl-5H-pyrimido[5,4-b]indole | 4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-8-fluoro-5H-pyrimido[5,4-b]indole | 8-fluoro-4-(4-piperonylpiperazino)-5H-pyrimid[5,4-b]indole | MLS000078398 | SMR000040683 | cid_659623 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20FN5O2 |
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| Mol. Mass. | 405.4249 |
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| SMILES | Fc1ccc2[nH]c3c(ncnc3c2c1)N1CCN(Cc2ccc3OCOc3c2)CC1 |
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| Structure | 
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