Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | P2X purinoceptor 3 | ||
| Ligand | BDBM266616 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Human P2X3 Receptor Inhibition Assay | ||
| pH | 7.5±n/a | ||
| IC50 | 2.00±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kai, H; Horiguchi, T; Asahi, K; Fujii, Y Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same US Patent US9718790 Publication Date 8/1/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| P2X purinoceptor 3 | |||
| Name: | P2X purinoceptor 3 | ||
| Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa | ||
| Type: | Protein | ||
| Mol. Mass.: | 44292.02 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P56373 | ||
| Residue: | 397 | ||
| Sequence: |
| ||
| BDBM266616 | |||
| n/a | |||
| Name | BDBM266616 | ||
| Synonyms: | US9718790, I-2350 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H27N5O3S | ||
| Mol. Mass. | 441.546 | ||
| SMILES | CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccsn3)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O |r,wU:22.23,wD:25.27,(5.96,1.13,;4.62,1.9,;3.29,1.13,;1.96,1.9,;1.96,3.44,;.62,1.13,;.62,-.41,;-.71,-1.18,;-2.04,-.41,;-2.04,1.13,;-3.38,1.9,;-4.71,1.13,;-6.05,1.9,;-6.05,3.44,;-4.8,4.34,;-5.28,5.8,;-6.82,5.8,;-7.29,4.34,;-4.71,-.41,;-3.38,-1.18,;1.96,-1.18,;1.96,-2.72,;3.29,-3.49,;4.62,-2.72,;5.96,-3.49,;5.96,-5.03,;7.29,-5.8,;4.62,-5.8,;3.29,-5.03,;3.29,-.41,;4.62,-1.18,)| | ||
| Structure | 
| ||