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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | P2X purinoceptor 3 | ||
| Ligand | BDBM266759 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Human P2X3 Receptor Inhibition Assay | ||
| pH | 7.5±n/a | ||
| IC50 | 1.000±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kai, H; Horiguchi, T; Asahi, K; Fujii, Y Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same US Patent US9718790 Publication Date 8/1/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| P2X purinoceptor 3 | |||
| Name: | P2X purinoceptor 3 | ||
| Synonyms: | ATP receptor | Glucocorticoid receptor | P2RX3 | P2RX3_HUMAN | P2X purinoceptor 3 | P2X purinoceptor 3 (P2RX3) | P2X purinoceptor 3 (P2X3) | P2X3 | P2X3 purinoceptor | Purinergic receptor | p2x3 + hsa | ||
| Type: | Protein | ||
| Mol. Mass.: | 44292.02 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P56373 | ||
| Residue: | 397 | ||
| Sequence: |
| ||
| BDBM266759 | |||
| n/a | |||
| Name | BDBM266759 | ||
| Synonyms: | US9718790, I-2494 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H28N6O3 | ||
| Mol. Mass. | 460.5282 | ||
| SMILES | CCn1c(=O)[nH]\c(=N/c2ccc(Oc3cccc(n3)C#N)cc2)n(C[C@H]2CC[C@H](C)CC2)c1=O |r,wU:25.26,wD:28.30,(7.33,.38,;6,1.15,;4.67,.38,;3.33,1.15,;3.33,2.69,;2,.38,;2,-1.16,;.67,-1.93,;-.67,-1.16,;-2,-1.93,;-3.33,-1.16,;-3.33,.38,;-4.67,1.15,;-4.67,2.69,;-3.33,3.47,;-3.33,5,;-4.67,5.77,;-6,5,;-6,3.47,;-7.34,5.78,;-8.67,6.55,;-2,1.15,;-.67,.38,;3.33,-1.93,;3.33,-3.47,;4.67,-4.24,;6,-3.47,;7.33,-4.24,;7.33,-5.78,;8.67,-6.55,;6,-6.55,;4.67,-5.78,;4.67,-1.16,;6,-1.93,)| | ||
| Structure | 
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