| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 6 |
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| Ligand | BDBM31731 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors |
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| IC50 | 8600±600 nM |
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| Citation |  PubChem, PC MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Dual specificity protein phosphatase 6 |
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| Name: | Dual specificity protein phosphatase 6 |
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| Synonyms: | DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42303.19 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_16758752 |
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| Residue: | 381 |
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| Sequence: | MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
QLYFTAPSNQNVYQVDSLQST
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| BDBM31731 |
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| n/a |
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| Name | BDBM31731 |
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| Synonyms: | 4-[5-[(Z)-(1-ketothiazolo[3,2-a]benzimidazol-2-ylidene)methyl]-2-furyl]benzoic acid | 4-[5-[(Z)-(1-oxidanylidene-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid | 4-[5-[(Z)-(1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid | 4-[5-[(Z)-(1-oxo-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid | MLS-0091939.0001 | cid_2243732 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H12N2O4S |
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| Mol. Mass. | 388.396 |
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| SMILES | OC(=O)c1ccc(cc1)-c1ccc(\C=c2/sc3nc4ccccc4n3c2=O)o1 |
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| Structure | 
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