Ki Summary

Reaction Details

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Target

Neuropeptide Y receptor type 1

Ligand

BDBM42532

Substrate/Competitor

n/a

Meas. Tech.

Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism

IC50

4079±n/a nM

Citation

PubChem, PC Dose response counterscreen for neuropeptide Y receptor Y2 (NPY-Y2): Cell-based high throughput assay to measure NPY-Y1 antagonism PubChem Bioassay(2008)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Neuropeptide Y receptor type 1

Name:

Neuropeptide Y receptor type 1

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

44399.07

Organism:

Homo sapiens (Human)

Description:

NPY-Y1 NPY1R HUMAN::P25929

Residue:

384

Sequence:

MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI

BDBM42532

n/a

Name

BDBM42532

Synonyms:

2-[1-[(Z)-1-(4-chlorobenzoyl)-2-(2-furyl)vinyl]-2-pyridylidene]malononitrile | 2-[1-[(Z)-3-(4-chlorophenyl)-1-(2-furanyl)-3-oxoprop-1-en-2-yl]-2-pyridinylidene]propanedinitrile | 2-[1-[(Z)-3-(4-chlorophenyl)-1-(furan-2-yl)-3-oxidanylidene-prop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile | 2-[1-[(Z)-3-(4-chlorophenyl)-1-(furan-2-yl)-3-oxoprop-1-en-2-yl]pyridin-2-ylidene]propanedinitrile | 2-{1-[(Z)-1-(4-Chloro-benzoyl)-2-furan-2-yl-vinyl]-1H-pyridin-2-ylidene}-malononitrile | MLS000589524 | SMR000213008 | cid_5806576

Type

Small organic molecule

Emp. Form.

C21H12ClN3O2

Mol. Mass.

373.792

SMILES

Clc1ccc(cc1)C(=O)C(=C\c1ccco1)\N1C=CC=CC1=C(C#N)C#N |c:19,21|

Structure