| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor coactivator 1 |
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| Ligand | BDBM37968 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) |
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| EC50 | >79370±n/a nM |
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| Citation |  PubChem, PC Dose response biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nuclear receptor coactivator 1 |
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| Name: | Nuclear receptor coactivator 1 |
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| Synonyms: | BHLHE74 | Class E basic helix-loop-helix protein 74 | NCOA1 | NCOA1_HUMAN | NCoA-1 | Nuclear receptor coactivator 1 | Protein Hin-2 | RIP160 | Renal carcinoma antigen NY-REN-52 | SRC-1 | SRC1 | Steroid receptor coactivator 1 | nuclear receptor coactivator 1 isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 156749.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_759690 |
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| Residue: | 1441 |
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| Sequence: | MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL
SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL
DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG
VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ
SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF
QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG
IHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINR
QQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTG
ISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS
LQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDN
SSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSC
TGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVS
VTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQ
MDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAV
TSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAIN
QSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKL
VQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGT
MPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQF
AATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSF
GNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN
RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI
PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS
MAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTE
ADGTQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLT
E
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| BDBM37968 |
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| n/a |
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| Name | BDBM37968 |
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| Synonyms: | 3-Benzylsulfanyl-5-methyl-[1,2,4]triazol-4-ylamine | 3-benzylsulfanyl-5-methyl-1,2,4-triazol-4-amine | 3-methyl-5-(phenylmethylsulfanyl)-1,2,4-triazol-4-amine | 3-methyl-5-(phenylmethylthio)-1,2,4-triazol-4-amine | MLS000072194 | SMR000009237 | [3-(benzylthio)-5-methyl-1,2,4-triazol-4-yl]amine | cid_647885 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12N4S |
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| Mol. Mass. | 220.294 |
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| SMILES | Cc1nnc(SCc2ccccc2)n1N |
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| Structure | 
|
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