| Reaction Details |
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 | Report a problem with these data |
| Target | Ras-related protein Rab-2A |
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| Ligand | BDBM43231 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype |
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| EC50 | 3638±n/a nM |
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| Citation |  PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Ras-related protein Rab-2A |
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| Name: | Ras-related protein Rab-2A |
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| Synonyms: | RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A. |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23545.28 |
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| Organism: | Canis lupus familiaris |
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| Description: | gi_46577642 |
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| Residue: | 212 |
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| Sequence: | MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIW
DTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNK
SDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINN
EANGIKIGPQHAATNATHAGNQGGQQAGGGCC
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| BDBM43231 |
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| n/a |
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| Name | BDBM43231 |
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| Synonyms: | (E)-3-(1-benzyl-3-thiophen-2-ylpyrazol-4-yl)prop-2-enoic acid | (E)-3-[1-(phenylmethyl)-3-thiophen-2-yl-4-pyrazolyl]-2-propenoic acid | (E)-3-[1-(phenylmethyl)-3-thiophen-2-yl-pyrazol-4-yl]prop-2-enoic acid | (E)-3-[1-benzyl-3-(2-thienyl)pyrazol-4-yl]acrylic acid | MLS001002570 | SMR000369092 | cid_2554530 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N2O2S |
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| Mol. Mass. | 310.37 |
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| SMILES | OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1cccs1 |
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| Structure | 
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