| Reaction Details |
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 | Report a problem with these data |
| Target | DNA-directed RNA polymerase subunit beta |
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| Ligand | BDBM43327 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | RNA polymerase SAR |
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| IC50 | >50000±n/a nM |
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| Citation |  PubChem, PC RNA polymerase SAR PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA-directed RNA polymerase subunit beta |
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| Name: | DNA-directed RNA polymerase subunit beta |
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| Synonyms: | RNA polymerase beta subunit (EC 2.7.7.6) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 150595.80 |
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| Organism: | Escherichia coli |
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| Description: | A0A0E2LB94 |
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| Residue: | 1342 |
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| Sequence: | MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQ
SYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQ
EVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYR
GSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME
LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKD
YIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRL
SALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGIL
SKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS
LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTR
ERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVT
DEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQV
VSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR
GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERG
DVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVS
RDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEK
LLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL
SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDE
LKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKIN
PIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAK
LREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK
LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLG
GKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
ESFNVLLKEIRSLGINIELEDE
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| BDBM43327 |
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| n/a |
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| Name | BDBM43327 |
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| Synonyms: | 1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-1-naphthalenyl)urea | 1-(2,5-dimethoxyphenyl)-3-(4-hydroxy-1-naphthyl)urea | 1-(2,5-dimethoxyphenyl)-3-(4-hydroxynaphthalen-1-yl)urea | 1-(2,5-dimethoxyphenyl)-3-(4-oxidanylnaphthalen-1-yl)urea | PC-0626772 | PCMD-CC-PAB-238 | cid_16738602 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18N2O4 |
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| Mol. Mass. | 338.3572 |
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| SMILES | COc1ccc(OC)c(NC(=O)Nc2ccc(O)c3ccccc23)c1 |
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| Structure | 
|
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