Reaction Details |
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Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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Ligand | BDBM43573 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response cell-based assay to measure STAT3 activation |
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IC50 | 5674±n/a nM |
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Citation | PubChem, PC Dose response cell-based assay to measure STAT3 activation PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Signal transducer and activator of transcription 3 [702-738,740-752] |
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Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
Synonyms: | APRF | STAT3 | STAT3_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 5263.93 |
Organism: | Homo sapiens (Human) |
Description: | gi_13272532 |
Residue: | 50 |
Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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BDBM43573 |
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n/a |
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Name | BDBM43573 |
Synonyms: | 6-({[4-(3,4-dihydro-1(2H)-quinolinylsulfonyl)phenyl]amino}carbonyl)-3-cyclohexene-1-carboxylic acid | 6-[[4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)anilino]-oxomethyl]-1-cyclohex-3-enecarboxylic acid | 6-[[4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)phenyl]carbamoyl]cyclohex-3-ene-1-carboxylic acid | MLS000051782 | SMR000080802 | cid_2971528 |
Type | Small organic molecule |
Emp. Form. | C23H24N2O5S |
Mol. Mass. | 440.512 |
SMILES | OC(=O)C1CC=CCC1C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCCc2ccccc12 |c:5| |
Structure |
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