| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase XIAP |
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| Ligand | BDBM44271 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of Antagonists of IAP-family anti-apoptotic proteins |
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| IC50 | 4300±900 nM |
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| Citation |  PubChem, PC SAR analysis of Antagonists of IAP-family anti-apoptotic proteins PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| E3 ubiquitin-protein ligase XIAP |
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| Name: | E3 ubiquitin-protein ligase XIAP |
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| Synonyms: | API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 56685.27 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P98170 |
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| Residue: | 497 |
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| Sequence: | MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP
SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD
SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK
CPMCYTVITFKQKIFMS
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| BDBM44271 |
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| n/a |
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| Name | BDBM44271 |
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| Synonyms: | (2S)-N-[(2S)-1-[(2S)-2-[(2,2-diphenylhydrazinyl)-oxomethyl]-1-pyrrolidinyl]-3-methyl-1-oxobutan-2-yl]-2-(methylamino)propanamide;formic acid | (2S)-N-[(2S)-1-[(2S)-2-[(diphenylamino)carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxidanylidene-butan-2-yl]-2-(methylamino)propanamide;methanoic acid | MLS-0391004.0001 | cid_25241663 | formic acid;(2S)-2-(methylamino)-N-[(1S)-2-methyl-1-[(2S)-2-[(N-phenylanilino)carbamoyl]pyrrolidine-1-carbonyl]propyl]propionamide | formic acid;(2S)-2-(methylamino)-N-[(2S)-3-methyl-1-oxo-1-[(2S)-2-[(N-phenylanilino)carbamoyl]pyrrolidin-1-yl]butan-2-yl]propanamide |
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| Type | Small organic molecule |
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| Emp. Form. | C26H35N5O3 |
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| Mol. Mass. | 465.5878 |
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| SMILES | CN[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NN(c1ccccc1)c1ccccc1 |
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| Structure | 
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