| Reaction Details |
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 | Report a problem with these data |
| Target | Ephrin type-A receptor 4 |
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| Ligand | BDBM44442 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists |
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| IC50 | >100000±n/a nM |
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| Citation |  PubChem, PC Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ephrin type-A receptor 4 |
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| Name: | Ephrin type-A receptor 4 |
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| Synonyms: | EPHA4_MOUSE | Eph receptor A4 | Epha4 | Sek | Sek1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 109812.17 |
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| Organism: | Mus musculus |
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| Description: | gi_34328113 |
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| Residue: | 986 |
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| Sequence: | MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
DEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
TFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
DVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDASCAKCPPHSYSV
WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVS
KYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNT
ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAIT
HQNKILSSVQAMRTQMQQMHGRMVPV
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| BDBM44442 |
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| n/a |
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| Name | BDBM44442 |
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| Synonyms: | 2-(1-methyl-2-benzimidazolyl)-2-[4-oxo-3-prop-2-enyl-5-[(3,4,5-trimethoxyphenyl)methylidene]-2-thiazolidinylidene]acetonitrile | 2-(1-methylbenzimidazol-2-yl)-2-[4-oxidanylidene-3-prop-2-enyl-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-2-ylidene]ethanenitrile | 2-(1-methylbenzimidazol-2-yl)-2-[4-oxo-3-prop-2-enyl-5-[(3,4,5-trimethoxyphenyl)methylidene]-1,3-thiazolidin-2-ylidene]acetonitrile | 2-[3-allyl-4-keto-5-(3,4,5-trimethoxybenzylidene)thiazolidin-2-ylidene]-2-(1-methylbenzimidazol-2-yl)acetonitrile | MLS000098330 | SMR000062493 | cid_2998243 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24N4O4S |
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| Mol. Mass. | 488.558 |
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| SMILES | COc1cc(C=c2s\c(=C(\C#N)c3nc4ccccc4n3C)n(CC=C)c2=O)cc(OC)c1OC |
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| Structure | 
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