| Reaction Details |
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 | Report a problem with these data |
| Target | Ephrin type-A receptor 4 |
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| Ligand | BDBM44500 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists |
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| IC50 | 11400±n/a nM |
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| Citation |  PubChem, PC Colorimetric assay for HTS discovery of chemical inhibitors of EphA4 receptor antagonists PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ephrin type-A receptor 4 |
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| Name: | Ephrin type-A receptor 4 |
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| Synonyms: | EPHA4_MOUSE | Eph receptor A4 | Epha4 | Sek | Sek1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 109812.17 |
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| Organism: | Mus musculus |
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| Description: | gi_34328113 |
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| Residue: | 986 |
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| Sequence: | MAGIFYFILFSFLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
DEKNTPIRTYQVCNVMEASQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
TFNLYYYESDNDKERFIRESQFGKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
DVPKMYCGADGEWLVPIGNCLCNAGHEEQNGECQACKIGYYKALSTDASCAKCPPHSYSV
WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTRVSITDLLAHTNYTFEIWAVNGVS
KYNPSPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGSESSRPNT
ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHMSQDDLARIGITAIT
HQNKILSSVQAMRTQMQQMHGRMVPV
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| BDBM44500 |
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| n/a |
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| Name | BDBM44500 |
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| Synonyms: | MLS000544060 | N-[(Z)-1-(1-naphthylcarbamoyl)-2-(4-nitrophenyl)vinyl]benzamide | N-[(Z)-3-(1-naphthalenylamino)-1-(4-nitrophenyl)-3-oxoprop-1-en-2-yl]benzamide | N-[(Z)-3-(naphthalen-1-ylamino)-1-(4-nitrophenyl)-3-oxidanylidene-prop-1-en-2-yl]benzamide | N-[(Z)-3-(naphthalen-1-ylamino)-1-(4-nitrophenyl)-3-oxoprop-1-en-2-yl]benzamide | N-{2-{4-nitrophenyl}-1-[(1-naphthylamino)carbonyl]vinyl}benzamide | SMR000163674 | cid_6504838 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H19N3O4 |
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| Mol. Mass. | 437.4468 |
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| SMILES | [O-][N+](=O)c1ccc(\C=C(/NC(=O)c2ccccc2)C(=O)Nc2cccc3ccccc23)cc1 |
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| Structure | 
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