Reaction Details |
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Target | Bcl-2-like protein 10 [11-204] |
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Ligand | BDBM32262 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. |
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EC50 | 30660±n/a nM |
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Citation | PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Bcl-2-like protein 10 [11-204] |
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Name: | Bcl-2-like protein 10 [11-204] |
Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 21981.77 |
Organism: | Homo sapiens (Human) |
Description: | gi_23396469 |
Residue: | 194 |
Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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BDBM32262 |
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n/a |
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Name | BDBM32262 |
Synonyms: | 5-benzyl-8-methyl-3-(methylthio)-[1,2,4]triazin[5,6-b]indole | 5-benzyl-8-methyl-3-methylsulfanyl-[1,2,4]triazino[5,6-b]indole | 8-methyl-3-(methylthio)-5-(phenylmethyl)-[1,2,4]triazino[5,6-b]indole | 8-methyl-3-methylsulfanyl-5-(phenylmethyl)-[1,2,4]triazino[5,6-b]indole | MLS000042505 | SMR000046397 | cid_6400963 |
Type | Small organic molecule |
Emp. Form. | C18H16N4S |
Mol. Mass. | 320.411 |
SMILES | CSc1nnc2c3cc(C)ccc3n(Cc3ccccc3)c2n1 |
Structure |
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