Reaction Details |
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Target | Bcl-2-like protein 10 [11-204] |
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Ligand | BDBM32289 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. |
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EC50 | 17800±n/a nM |
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Citation | PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Bcl-2-like protein 10 [11-204] |
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Name: | Bcl-2-like protein 10 [11-204] |
Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 21981.77 |
Organism: | Homo sapiens (Human) |
Description: | gi_23396469 |
Residue: | 194 |
Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
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BDBM32289 |
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n/a |
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Name | BDBM32289 |
Synonyms: | 2-[(1-prop-2-ynyl-3-indolyl)methylidene]indene-1,3-dione | 2-[(1-prop-2-ynylindol-3-yl)methylidene]indene-1,3-dione | 2-[(1-propargylindol-3-yl)methylene]indane-1,3-quinone | 2-{[1-(2-propyn-1-yl)-1H-indol-3-yl]methylene}-1H-indene-1,3(2H)-dione | MLS000574697 | SMR000196125 | cid_807202 |
Type | Small organic molecule |
Emp. Form. | C21H13NO2 |
Mol. Mass. | 311.3334 |
SMILES | O=[#6]-1\[#6](=[#6]\c2cn(-[#6]C#C)c3ccccc23)-[#6](=O)-c2ccccc-12 |
Structure |
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