| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 10 [11-204] |
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| Ligand | BDBM46296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. |
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| EC50 | 820±n/a nM |
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| Citation |  PubChem, PC Multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B protein. PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 10 [11-204] |
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| Name: | Bcl-2-like protein 10 [11-204] |
|---|
| Synonyms: | Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). | B2L10_HUMAN | BCL-B | BCL2L10 | BCLB | BOO | DIVA |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21981.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_23396469 |
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| Residue: | 194 |
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| Sequence: | MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY
PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQ
EGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSC
LLTTAFIYLWTRLL
|
|
|
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| BDBM46296 |
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| n/a |
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| Name | BDBM46296 |
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| Synonyms: | (2-methoxyphenyl)-[4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)thiazol-2-yl]amine;hydrobromide | MLS000707342 | N-(2-methoxyphenyl)-4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-2-thiazolamine;hydrobromide | N-(2-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-amine;hydrobromide | SMR000288807 | cid_2877735 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15N5OS |
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| Mol. Mass. | 337.399 |
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| SMILES | COc1ccccc1Nc1nc(cs1)-c1c(C)nc2ncccn12 |
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| Structure | 
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