| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase D1 |
|---|
| Ligand | BDBM32352 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence polarization assay for PKD inhibitiors-interference assay-57K HTS campaign |
|---|
| IC50 | >50000±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence polarization assay for PKD inhibitiors-interference assay-57K HTS campaign PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Serine/threonine-protein kinase D1 |
|---|
| Name: | Serine/threonine-protein kinase D1 |
|---|
| Synonyms: | KPCD1_HUMAN | PKD | PKD1 | PRKCM | PRKD1 | Protein kinase C mu | Protein kinase C mu type | Protein kinase C mu type (PRKD1) | Protein kinase C, PKC; classical/novel | Protein kinase D | Protein kinase D (PRKD1) | Serine/threonine-protein kinase D1 (PKD1) | nPKC-D1 | nPKC-mu |
|---|
| Type: | Serine/threonine-protein kinase |
|---|
| Mol. Mass.: | 101705.07 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_115529463 |
|---|
| Residue: | 912 |
|---|
| Sequence: | MSAPPVLRPPSPLLPVAAAAAAAAAALVPGSGPGPAPFLAPVAAPVGGISFHLQIGLSRE
PVLLLQDSSGDYSLAHVREMACSIVDQKFPECGFYGMYDKILLFRHDPTSENILQLVKAA
SDIQEGDLIEVVLSASATFEDFQIRPHALFVHSYRAPAFCDHCGEMLWGLVRQGLKCEGC
GLNYHKRCAFKIPNNCSGVRRRRLSNVSLTGVSTIRTSSAELSTSAPDEPLLQKSPSESF
IGREKRSNSQSYIGRPIHLDKILMSKVKVPHTFVIHSYTRPTVCQYCKKLLKGLFRQGLQ
CKDCRFNCHKRCAPKVPNNCLGEVTINGDLLSPGAESDVVMEEGSDDNDSERNSGLMDDM
EEAMVQDAEMAMAECQNDSGEMQDPDPDHEDANRTISPSTSNNIPLMRVVQSVKHTKRKS
STVMKEGWMVHYTSKDTLRKRHYWRLDSKCITLFQNDTGSRYYKEIPLSEILSLEPVKTS
ALIPNGANPHCFEITTANVVYYVGENVVNPSSPSPNNSVLTSGVGADVARMWEIAIQHAL
MPVIPKGSSVGTGTNLHRDISVSISVSNCQIQENVDISTVYQIFPDEVLGSGQFGIVYGG
KHRKTGRDVAIKIIDKLRFPTKQESQLRNEVAILQNLHHPGVVNLECMFETPERVFVVME
KLHGDMLEMILSSEKGRLPEHITKFLITQILVALRHLHFKNIVHCDLKPENVLLASADPF
PQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGT
FPFNEDEDIHDQIQNAAFMYPPNPWKEISHEAIDLINNLLQVKMRKRYSVDKTLSHPWLQ
DYQTWLDLRELECKIGERYITHESDDLRWEKYAGEQGLQYPTHLINPSASHSDTPETEET
EMKALGERVSIL
|
|
|
|---|
| BDBM32352 |
|---|
| n/a |
|---|
| Name | BDBM32352 |
|---|
| Synonyms: | 2-(3-besylpropanoylimino)-3,4-dimethyl-4-thiazoline-5-carboxylic acid ethyl ester | 2-[3-(benzenesulfonyl)-1-oxopropyl]imino-3,4-dimethyl-5-thiazolecarboxylic acid ethyl ester | MLS000624279 | SMR000323584 | cid_7243149 | ethyl 2-[3-(benzenesulfonyl)propanoylimino]-3,4-dimethyl-1,3-thiazole-5-carboxylate | ethyl 3,4-dimethyl-2-[3-(phenylsulfonyl)propanoylimino]-1,3-thiazole-5-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H20N2O5S2 |
|---|
| Mol. Mass. | 396.481 |
|---|
| SMILES | CCOC(=O)c1sc(=NC(=O)CCS(=O)(=O)c2ccccc2)n(C)c1C |w:8.8| |
|---|
| Structure | 
|
|---|
Search and Browse
