| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Ligand | BDBM43519 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition |
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| IC50 | >55700±n/a nM |
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| Citation |  PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Synonyms: | APRF | STAT3 | STAT3_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 5263.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13272532 |
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| Residue: | 50 |
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| Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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| BDBM43519 |
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| n/a |
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| Name | BDBM43519 |
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| Synonyms: | 3-[[4-(2-fluorophenyl)-1,3-thiazol-2-yl]methyl]-2-[(4-methylpiperazin-1-yl)methyl]quinazolin-4-one | 3-[[4-(2-fluorophenyl)-2-thiazolyl]methyl]-2-[(4-methyl-1-piperazinyl)methyl]-4-quinazolinone | 3-[[4-(2-fluorophenyl)thiazol-2-yl]methyl]-2-[(4-methylpiperazino)methyl]quinazolin-4-one | MLS000416421 | SMR000264258 | cid_4302443 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24FN5OS |
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| Mol. Mass. | 449.544 |
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| SMILES | CN1CCN(Cc2nc3ccccc3c(=O)n2Cc2nc(cs2)-c2ccccc2F)CC1 |
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| Structure | 
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