| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Ligand | BDBM43454 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition |
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| IC50 | 34580±n/a nM |
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| Citation |  PubChem, PC Dose response counterscreen for STAT1 inhibitors: cell-based high throughput assay to measure STAT3 inhibition PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Name: | Signal transducer and activator of transcription 3 [702-738,740-752] |
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| Synonyms: | APRF | STAT3 | STAT3_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 5263.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13272532 |
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| Residue: | 50 |
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| Sequence: | AAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNGEGAEPSAGGQF
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| BDBM43454 |
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| n/a |
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| Name | BDBM43454 |
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| Synonyms: | MLS000729575 | N-(2-chloranylpyridin-3-yl)-4-[4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonyl-butanamide | N-(2-chloro-3-pyridinyl)-4-[[4-(2-methoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinyl]sulfonyl]butanamide | N-(2-chloro-3-pyridyl)-4-[4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonyl-butyramide | N-(2-chloropyridin-3-yl)-4-[4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonylbutanamide | N-(2-chloropyridin-3-yl)-4-{[4-(2-methoxyphenyl)-6-(trifluoromethyl)pyrimidin-2-yl]sulfonyl}butanamide | SMR000307852 | cid_3441150 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18ClF3N4O4S |
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| Mol. Mass. | 514.905 |
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| SMILES | COc1ccccc1-c1cc(nc(n1)S(=O)(=O)CCCC(=O)Nc1cccnc1Cl)C(F)(F)F |
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| Structure | 
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