| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, germ cell type |
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| Ligand | BDBM46076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation |
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| IC50 | 1040±n/a nM |
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| Citation |  PubChem, PC Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase confirmation PubChem Bioassay(2009)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Alkaline phosphatase, germ cell type |
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| Name: | Alkaline phosphatase, germ cell type |
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| Synonyms: | ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57374.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_29964 |
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| Residue: | 532 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLG
DGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLC
GVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDY
SQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRD
STLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERA
GQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVL
KDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHV
MAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
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| BDBM46076 |
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| n/a |
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| Name | BDBM46076 |
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| Synonyms: | 3-[2-(3,4-dihydroxyphenyl)ethyl]-8-fluoro-5H-pyrimid[5,4-b]indol-4-one | 3-[2-(3,4-dihydroxyphenyl)ethyl]-8-fluoro-5H-pyrimido[5,4-b]indol-4-one | 3-[2-[3,4-bis(oxidanyl)phenyl]ethyl]-8-fluoranyl-5H-pyrimido[5,4-b]indol-4-one | MLS-0390860.0001 | cid_932151 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14FN3O3 |
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| Mol. Mass. | 339.3205 |
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| SMILES | Oc1ccc(CCn2cnc3c4cc(F)ccc4[nH]c3c2=O)cc1O |
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| Structure | 
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