Reaction Details | |||
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Target | Eukaryotic translation initiation factor 4 gamma 1 | ||
Ligand | BDBM43265 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation | ||
IC50 | 15658.39968±n/a nM | ||
Citation | PubChem, PC Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation PubChem Bioassay(2009)[AID] | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Eukaryotic translation initiation factor 4 gamma 1 | |||
Name: | Eukaryotic translation initiation factor 4 gamma 1 | ||
Synonyms: | EIF4F | EIF4G | EIF4G1 | EIF4GI | IF4G1_HUMAN | eukaryotic translation initiation factor 4 gamma, 1 isoform 4 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 175455.17 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q04637 | ||
Residue: | 1599 | ||
Sequence: |
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BDBM43265 | |||
n/a | |||
Name | BDBM43265 | ||
Synonyms: | 9-(2,5-dimethoxyphenyl)-2,6,7-trihydroxy-3-xanthenone | 9-(2,5-dimethoxyphenyl)-2,6,7-trihydroxy-3H-xanthen-3-one | 9-(2,5-dimethoxyphenyl)-2,6,7-trihydroxy-fluorone | 9-(2,5-dimethoxyphenyl)-2,6,7-trihydroxyxanthen-3-one | 9-(2,5-dimethoxyphenyl)-2,6,7-tris(oxidanyl)xanthen-3-one | MLS000577889 | SMR000197599 | cid_2930652 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H16O7 | ||
Mol. Mass. | 380.3475 | ||
SMILES | COc1ccc(OC)c(c1)-c1c2cc(O)c(O)cc2oc2cc(=O)c(O)cc12 |(6.68,5.12,;6.68,3.58,;8.01,2.81,;9.34,3.58,;10.68,2.81,;10.68,1.27,;12.01,.5,;13.35,1.27,;9.34,.5,;8.01,1.27,;9.34,-1.04,;10.68,-1.81,;12.06,-.99,;13.45,-1.78,;14.78,-1.01,;13.45,-3.39,;14.78,-4.16,;12.06,-4.18,;10.68,-3.35,;9.34,-4.12,;8.01,-3.35,;6.63,-4.18,;5.24,-3.39,;3.91,-4.16,;5.24,-1.78,;3.91,-1.01,;6.63,-.99,;8.01,-1.81,)| | ||
Structure |