BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTranscription factor p65
LigandBDBM49183
Substrate/Competitorn/a
Meas. Tech.Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50 3248±n/a nM
Citation PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Transcription factor p65
Name:Transcription factor p65
Synonyms:NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:Enzyme
Mol. Mass.:60211.92
Organism:Homo sapiens (Human)
Description:Q04206
Residue:551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM49183
n/a
NameBDBM49183
Synonyms:(6E)-6-(5-butyl-1H-pyridin-2-ylidene)-3-methyl-1-cyclohexa-2,4-dienone | (6E)-6-(5-butyl-1H-pyridin-2-ylidene)-3-methyl-cyclohexa-2,4-dien-1-one | (6E)-6-(5-butyl-1H-pyridin-2-ylidene)-3-methylcyclohexa-2,4-dien-1-one | 2-(5-Butyl-pyridin-2-yl)-5-methyl-phenol | MLS000068246 | SMR000001112 | cid_6097138
TypeSmall organic molecule
Emp. Form.C16H19NO
Mol. Mass.241.3282
SMILESCCCCc1ccc(nc1)-c1ccc(C)cc1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: