| Reaction Details |
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 | Report a problem with these data |
| Target | Transcription factor p65 |
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| Ligand | BDBM49187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response |
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| EC50 | 1170±n/a nM |
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| Citation |  PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Transcription factor p65 |
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| Name: | Transcription factor p65 |
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| Synonyms: | NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 60211.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q04206 |
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| Residue: | 551 |
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| Sequence: | MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
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| BDBM49187 |
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| n/a |
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| Name | BDBM49187 |
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| Synonyms: | 4-Methyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide | MLS000027847 | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methyl-5-thieno[3,2-b]pyrrolecarboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methyl-thieno[3,2-b]pyrrole-5-carboxamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methylthieno[3,2-b]pyrrole-5-carboxamide | SMR000007362 | cid_654316 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2O3S |
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| Mol. Mass. | 314.359 |
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| SMILES | Cn1c(cc2sccc12)C(=O)Nc1ccc2OCCOc2c1 |
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| Structure | 
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