BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTranscription factor p65
LigandBDBM49190
Substrate/Competitorn/a
Meas. Tech.Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50 14523±n/a nM
Citation PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Transcription factor p65
Name:Transcription factor p65
Synonyms:NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:Enzyme
Mol. Mass.:60211.92
Organism:Homo sapiens (Human)
Description:Q04206
Residue:551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM49190
n/a
NameBDBM49190
Synonyms:(3-Cyano-7-ethoxy-quinolin-2-ylsulfanyl)-acetic acid methyl ester | 2-[(3-cyano-7-ethoxy-2-quinolinyl)thio]acetic acid methyl ester | 2-[(3-cyano-7-ethoxy-2-quinolyl)thio]acetic acid methyl ester | MLS000068863 | SMR000002488 | cid_656128 | methyl 2-(3-cyano-7-ethoxy-quinolin-2-yl)sulfanylethanoate | methyl 2-(3-cyano-7-ethoxyquinolin-2-yl)sulfanylacetate
TypeSmall organic molecule
Emp. Form.C15H14N2O3S
Mol. Mass.302.348
SMILESCCOc1ccc2cc(C#N)c(SCC(=O)OC)nc2c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: