| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transcription factor p65 |
|---|
| Ligand | BDBM49197 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response |
|---|
| EC50 | 93528±n/a nM |
|---|
| Citation |  PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Transcription factor p65 |
|---|
| Name: | Transcription factor p65 |
|---|
| Synonyms: | NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 60211.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q04206 |
|---|
| Residue: | 551 |
|---|
| Sequence: | MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
|
|
|
|---|
| BDBM49197 |
|---|
| n/a |
|---|
| Name | BDBM49197 |
|---|
| Synonyms: | 6-[(4-chlorophenyl)sulfanylmethyl]-3-methyl-imidazo[2,1-b][1,3]thiazole | 6-[(4-chlorophenyl)sulfanylmethyl]-3-methylimidazo[2,1-b][1,3]thiazole | 6-[[(4-chlorophenyl)thio]methyl]-3-methyl-imidazo[2,1-b]thiazole | 6-[[(4-chlorophenyl)thio]methyl]-3-methylimidazo[2,1-b]thiazole | MLS000068784 | SMR000034119 | cid_658793 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H11ClN2S2 |
|---|
| Mol. Mass. | 294.823 |
|---|
| SMILES | Cc1csc2nc(CSc3ccc(Cl)cc3)cn12 |
|---|
| Structure | 
|
|---|
Search and Browse
