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TargetTranscription factor p65
LigandBDBM39441
Substrate/Competitorn/a
Meas. Tech.Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response
EC50 2197±n/a nM
Citation PubChem, PC Name: High Throughput Screen to Identify Compounds that increase expression of NF-kB in Human Neuronal Cells - Dose Response PubChem Bioassay(2008)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Transcription factor p65
Name:Transcription factor p65
Synonyms:NFKB3 | Nuclear factor NF-kappa-B | Nuclear factor NF-kappa-B p65 subunit | RELA | TF65_HUMAN | v-rel reticuloendotheliosis viral oncogene homolog A isoform 1
Type:Enzyme
Mol. Mass.:60211.92
Organism:Homo sapiens (Human)
Description:Q04206
Residue:551
Sequence:
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPT
IKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQC
VKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLS
HPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFS
QADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEE
KRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINY
DEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQA
VAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQ
GIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADM
DFSALLSQISS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM39441
n/a
NameBDBM39441
Synonyms:(2Z)-2-[1-(3-hydroxyanilino)ethylidene]-1-benzothiophen-3-one | (2Z)-2-[1-(3-hydroxyanilino)ethylidene]benzothiophen-3-one | (2Z)-2-[1-[(3-hydroxyphenyl)amino]ethylidene]-1-benzothiophen-3-one | MLS000027586 | SMR000057767 | cid_5389102
TypeSmall organic molecule
Emp. Form.C16H13NO2S
Mol. Mass.283.345
SMILESCC(=Nc1cccc(O)c1)c1sc2ccccc2c1O |w:2.2|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: